-
- Home
- Journals
- Journal of Biosciences
-
B K Bachhawat
Articles written in Journal of Biosciences
-
-
Volume 5 Issue 2 June 1983 pp 155-162
S Mohan D Thambi Dorai S Srimal B K Bachhawat M K Das
The binding affinities of some ligands towards the sialic acid-specific lectin carcinoscorpin, from hemolymph of the horseshoe crab
Carcinoscorpius rotundacauda have been determined by protein fluorescence quenching in presence of ligands. Among the ligands studied, the disaccharide O-(N-acetylneuraminyl)-(2→6)-2-acetamido-2-deoxy-D-galactitol has the highest Ka(l.15 × 106 M-1) for carcinoscorpin. Studies on the effect of pH on Ka values of disaccharide suggests the possible involvement of amino acid residues having pKa values around 6.0 and 9.0 in the binding activity of carcinoscorpin. There were distinct changes in the accessibility of the fluorescent tryptophan residues of carcinoscorpin by ligand-binding as checked through potassium iodide quenching. -
Volume 6 Issue 6 December 1984 pp 811-816
Increased circulatory half-life of liposomes after conjunction with dextran
D Pain P K Das P Ghosh B K Bachhawat
Dextran was covalently coupled to neutral unilamellar liposomes. Dextran conjugated liposomes were cleared from the circulation at a much slower rate than unconjugated liposomes. The uptake of dextran conjugated liposomes by liver and spleen was also decreased. The amount of dextran on the surface of liposomes was found to be a determining factor for their stability in circulation. Dextran conjugated liposomes therefore may be a more effective way of controlled drug release
-
Volume 16 Issue 4 December 1991 pp 217-221
Tissue distribution and antileishmanial activity of liposomised Amphotericin-B in Balb/c mice§
Imran Ahmad Anshu Agarwal Ajay Pal P Y Guru B K Bachhawat C M Gupta
Antileishmanial activity and organ distribution of the antifungal drug Amphotericin-B in free and liposomised form have been studied in Balb/c mice infected with
Leishmania donovani . Results indicate that Amphotericin-B in the liposomised form is significantly more active than the free form. This increase in the activity is perhaps related to the reduced drug toxicity rather than the altered drug distribution at the site of infection.
-
-
Journal of Biosciences
Volume 48, 2023
All articles
Continuous Article Publishing mode
-
Journal of Biosciences | News
-
To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".
Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.
Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.
Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx
Posted on April 12, 2023< -
Editorial Note on Continuous Article Publication
Posted on July 25, 2019Click here for Editorial Note on CAP Mode
Forthcoming Special issue.
-