• TIRSO E FLORES-GUIA

      Articles written in Bulletin of Materials Science

    • Potential biomedical application of a new MOF based on a derived PET: synthesis and characterization

      DENIS A CABRERA-MUNGUIA M ILEANA LEÓN-CAMPOS JESUÚ A CLAUDIO-RIZO DORA A SOLÍS-CASADOS TIRSO E FLORES-GUIA LUCIA F CANO SALAZAR

      More Details Abstract Fulltext PDF

      Metal–organic frameworks (MOFs) are materials with a large surface area and antimicrobial properties are advantageous properties for the controlled release of molecules for biomedical applications. However, their synthesis is expensive and harmful to the environment due to the use of organic ligands and solvents. Thus, this work proposes the synthesis of a new MOF by hydrothermal method using water as the solvent, aluminium nitrate as a metallic source, and bis(2-hydroxyethyl) terephthalate (BHET) as organic ligand, obtained via glycolysis of polyethylene terephthalate (PET); and its comparison with MIL53-Al MOF, synthesized from terephthalic acid (BDC) as organic ligand. Both MOFs were characterized by XRD, ATR-FTIR, N$_2$ physisorption, TGA, SEM and XPS; besides their in vitro biocompatibility was tested by porcine fibroblasts viability. The results indicate that aluminium ions are coordinated to both carbonyl and hydroxyl functional groups of the BDC and BHET organic ligands. The new BHET-Al MOF shows higher thermal stability than MIL53-Al, it also exhibits a macroporous structure in comparison with the microporosity of the MIL53-Al. BHET-Al MOF is not cytotoxic for porcine dermal fibroblasts growing on its surface for up to 48 h of culture, thus, this innovative MOF is a promising material for the controlled release of drugs.

  • Bulletin of Materials Science | News

    • Dr Shanti Swarup Bhatnagar for Science and Technology

      Posted on October 12, 2020

      Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
      Chemical Sciences 2020

      Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
      Physical Sciences 2020

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2021-2022 Indian Academy of Sciences, Bengaluru.