Articles written in Bulletin of Materials Science
Volume 9 Issue 5 December 1987 pp 309-315
Soft tissue reaction to metals, ceramics and composites was investigated over a long period. Titanium, nitrided titanium, ruby, sapphire and carbon-carbon composite materials were used. Histological response was uniform for all materials despite their differing chemical and physical properties.
Volume 12 Issue 1 March 1989 pp 17-25
Smooth, perfectly spherical, highly hydrophilic microspheres have been prepared from crosslinked poly(methyl methacrylate) microspheres by alkaline hydrolysis in ethylene glycol at elevated temperatures. These microspheres absorb varying quantities of water depending upon the extent of hydrolysis. Subcutaneous implantation studies on rabbits demonstrated that the microspheres are biocompatible. Implantation studies in the renal arteries of dogs demonstrated the occlusion effect produced by the microspheres. Microspheres could be made radiopaque by the incorporation of barium sulphate. Potential uses envisaged for these microspheres in the biomedical area are that of artificial emboli for endovascular embolization and as microcarriers for the growth and propagation of anchorage dependent mammalian cells.
Volume 21 Issue 6 December 1998 pp 439-444 Biomaterials
Carbon in the form of pyrolytic carbon coating is used in a number of implantable medical devices. Carbon-reinforced carbon composite and other forms of diamond-like carbon coatings are being evaluated for their many potential biomedical applications. There is also a possibility of using carbon in fibre form. Though the possibility of using the fibre form of carbon in skeletal and dental implants has been recognized, a detailed study of tissue reaction to carbon fibre has not been reported so far. In this paper, we describe
Volume 42 | Issue 6
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