To utilize the potent pharmaceutical properties of curcumin (Cur) and gelatin-based materials in tissue regeneration, we fabricated a thermosensitive nanocomposite hydrogel based on pluronic-grafted gelatin (PG) and nanocurcumin (nCur) to enhance burn healing. In this method, the amphiphilic PG played a role as a surfactant to prepare and protect nanosized Cur particles, which could overcome the poor dissolution of the phytochemical. The synthesized PG was identified by ${}^1$H nuclear magnetic resonance. Depending on the amount of Cur, size distribution of the dispersed nCur ranged from $1.5\pm 0.5$to $16\pm 3.2$ nm as observed using transmission electron microscopy and dynamic light scattering. The nCur-dispersed PG solution formed nCur–PG nanocomposite hydrogel on warming up to 35$^{\circ}$C. Release profile indicated sustainable release of Cur from the injectable platform. Fibroblast cells were well proliferated on the nanocomposite hydrogel. The nCur–PGenhanced the healing process of second-degree burn wound. These results showed potential applications of the biomaterial in tissue regeneration.

The main objective of this study is the preparation of a polyethylene glycol (PEG)–Fe$_3$O$_4$/ZnO magnetic nanocomposite using a green sonochemical synthesis method with rambutan peel extract as a stabilizing agent for photocatalytic methylene blue (MB) degradation. The synthesized nanocomposites were characterized using field emission scanning electron microscopy, energy dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy(FTIR), X-ray diffraction and UV–visible methods. The field emission scanning electron microscopy results showed the size of nanocomposite was 20–30 nm and had the bandgap energy of 2.58 eV. The effects of the photocatalyst and process time were investigated. The kinetics were investigated, and the regeneration of the photocatalyst was evaluated. Kinetic experiments on MB degradation using the nanocomposite showed good agreement with the Langmuir–Hinshelwood model, and the photocatalyst could remove over 98% of the MB within 90 min.