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JOYSHREE MAJI
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Volume 43 All articles Published: 3 January 2020 Article ID 0025
Synthesis and evaluation of antibacterial properties of magnesium oxide nanoparticles
JOYSHREE MAJI SANJEEV PANDEY SOUMEN BASU
In this paper we studied the efficiency of magnesium oxide (MgO) nanoparticles with an average size of 27 nm synthesized by a simple soft chemical method, in killing both Gram negative and Gram positive pathogenic bacteria. The antibacterial activity was determined by a minimum inhibitory concentration technique, agar cup method and live count technique. These nanoparticles show the maximum antibacterial activity towards
Bacillus sp. in comparison withEscherichia coli. Transmission electron microscopy analyses of the treated-bacterial strains showed a morphological deformation with increased cell wall disruption. From the analysis of the antibacterial activity of MgO nanoparticles it is revealed that6 $\mu$g ml$^{−1}$ of dose is sufficient for killingBacillus sp. whereas it is 7.5 $\mu$g ml$^{−1}$ forE. coli. These doses may be used in medical application. MgO nanoparticles could be used as antibacterial agents after completion of successfulin vivo trials.
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Bulletin of Materials Science
Volume 43, 2020
All articles
Continuous Article Publishing mode
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Dr Shanti Swarup Bhatnagar for Science and Technology
Posted on October 12, 2020Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
Chemical Sciences 2020Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
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