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FARSHAD QALEKHANI
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Volume 45 All articles Published: 16 May 2022 Article ID 0088
AZAM CHAHARDOLI FARSHAD QALEKHANI YALDA SHOKOOHINIA ALI FATTAHI
The isolated and pure biological compounds have been widely used in natural-based nanoparticles, entailing applications in medicine, cosmetics and nutrition. In this study, the toxic effects (
in vitro ) and biomedical applications of isoimperatorin-mediated green synthesized silver nanoparticles (Iso-AgNPs) were investigated. Thein vitro antioxidant, antibacterial and cytotoxic potential were determined by using standard protocols. Besides, blood compatibility was determined by hemolysis and coagulation tests. Based on the obtained results, Iso-AgNPs showed enhanced antioxidant capacity in comparison with the crude isoimperatorin and were found effective against the pathogenic bacterial strains.Cell viability study reveals the safety of Iso-AgNPs on H1299 and MCF-7 cell lines, and no significant cytotoxicity was observed. The non-hemolytic effect of Iso-AgNPs on erythrocyte cells (RBCs) and the absence of coagulation indicate high blood compatibility of these nanoparticles, which make them unique in comparison to the other silver nanoparticles. Altogether, our finding confirms the biological advantages of Iso-AgNPs as a cyto- and blood-compatible antibacterial and antioxidant nano-metal.
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Bulletin of Materials Science
Volume 46, 2023
All articles
Continuous Article Publishing mode
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Bulletin of Materials Science | News
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Dr Shanti Swarup Bhatnagar for Science and Technology
Posted on October 12, 2020Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
Chemical Sciences 2020Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
Physical Sciences 2020 -
Editorial Note on Continuous Article Publication
Posted on July 25, 2019Click here for Editorial Note on CAP Mode
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