• M Appaswamy Rao

      Articles written in Proceedings – Animal Sciences

    • Durational effects of hemispaying on ovarian hypertrophy and estrous cycle in albino rats

      Saraswati B Patil M Appaswamy Rao

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      Ovarian hypertrophy is studied by hemispaying the rats for 7, 15, 20, 25 and 30 days. The compensatory hypertrophy of the ovary is calculated in relation to their respective sham operated controls. The maximum hypertrophy is observed 20 days after hemispaying, as indicated by ovarian weight and its histological observations. Thereafter the hypertrophic response though significant, decreases gradually, indicating that once the circulating estrogen secreted by the hypertrophied ovary comes to preoperative level, the pituitary gonadotrophin level also falls down. The hemispaying has no significant effect either on the duration or number of estrous cycle.

    • Intereuption of pregnancy by barbiturates in albino rats

      Saraswati B Patil M Appaswamy Rao

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      Barbiturates inhibit thelh surge and release of gonadotrophins (lh and fsh) and prolactin from the pituitary in rats and hamsters. In the present study administration of phenobarbital (7-5mg) or barbital sodium (20 mg) twice a day from day 8–11 interrupts the pregnancy in rats with little or no foetal survival. The ovaries and the uterus of these rats resemble those of non-pregnant rats when autopsied on day 20 of pregnancy. These results suggest that the failure of maintenance of pregnancy by barbiturate treatment may be due to the inhibition of luteotrophic hormones from the pituitary during the crucial period of pregnancy, resulting in the insufficient secretion and release of ovarian progesterone and also estrogen.

    • Implantation delay and nidation by progesterone in carrot seed (Daucus carota) extract treated albino rats

      B B Kaliwal R Nazeer Ahamed M Appaswamy Rao

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      In the present study the effect of petroleum ether extract of carrot seeds and progesterone on implantation have been investigated. 0·6 ml/100 g body weight of carrot seed extract was administered subcutaneously from days 1–7 of pregnancy and laparatomized on day 8. No implantation sites were observed. Thereafter graded doses of progesterone 2, 4 or 8 mg/100 g body weight was administered upto day 15 and autopsied on day 16. Two mg of progesterone did not show any effect. However, 4 mg of progesterone treated rats had smaller implantation sites compared to the controls whereas, 8 mg of progesterone was most effective with the result that in almost all the rats, delayed implantation was observed.

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