pp 1321-1323 Editorial
pp 1326-1326 Science Smiles
pp 1327-1332 General Article
Professor Gilbert Stork, the organic chemist and teacher parexcellence, passed away on 21 October 2017. His departuremarked the end of a hallowed era of classical organic synthesis.His extraordinary scholarship in organic chemistry,originality, and human qualities such as humility, kindness,warmth and concern for students, and humanity in general,sets him a class apart.
pp 1333-1341 General Article
On Tuesday, 02 October 2018, Arthur Ashkin of the UnitedStates, who pioneered a way of using light to manipulate physicalobjects, shared the first half of the 2018 Nobel Prize inPhysics. The second half was divided equally between G´erardMourou of France and Donna Strickland of Canada for theirmethod of generating high-intensity, ultra-short optical pulses.With this announcement, Donna Strickland, who was awardedthe Nobel for her work as a PhD student withG´erard Mourou,became the third woman to have ever won the Physics NobelPrize, and the 96-year-old Arthur Ashkin who was awardedfor his work on optical tweezers and their application to biologicalsystems, became the oldest Nobel Prize winner. Accordingto Nobel.org, the practical applications leading to thePrize in 2018 are tools made of light that have revolutionisedlaser physics – a discipline which in turn is represented bygenerations of advancements and not just a single example ofbrilliant work.
pp 1343-1358 General Article
The 2018 Nobel Prize for Chemistry rewards research on theuse of bacteria and viruses to generate and screen highly diverse protein sequences for improved catalytic and ligand-binding function. One half of the Prize was awarded to Professor Frances Arnold of the California Institute of Technology (California, USA). The other half was awarded jointlyto Professor George P Smith of the University of Missouri(Columbia, USA) and Professor Sir Gregory P Winter of theMedical Research Council’s Laboratory of Molecular Biology (Cambridge, UK). The three winners have been amongst the tallest of stalwarts in combinatorial approaches to protein engineering.
pp 1359-1366 General Article
The Nobel Prize in Physiology or Medicine for the year 2018was awarded to James P Allison of the United States andTasuku Honjo of Japan for their immense contributions towardsthe application of immunotherapy for the treatment ofcancer. To understand the ramifications of their discovery,we must first understand how the immune system works.
pp 1367-1373 General Article
Radio telescopes allow a 24 × 7 observation time window ofthose regions of the space which appear dark in the visibleregion. But, the major problem with a single radio telescopeis its poor resolution. In this article, the method of interferometryin radio astronomy is discussed by citing the exampleof a two-element interferometer. Interferometry providesimproved resolution.With a single telescope as well, the resolutioncan be improved for the radio sources along the eclipticwhich are smaller in angular spread as compared to theMoon. The theoretical principle behind the technique of occultationis discussed using its optical analog of diffraction.
pp 1375-1393 General Article
This article reviews the basic concepts of second quantizationas used in condensed matter physics. The Kitaev chain wasthe first system shown to exhibit Majorana zero modes, whichexhibit novel statistics and thus find enormous applications intopological quantum computation. Simple calculations of theband structure and density of states showing the presence ofMajorana zero modes are presented.
pp 1395-1410 General Article
The article explores the application of binary and ternarynumber systems to three classical mathematical puzzles –weight problem of Bachet deMeziriac, binary numbers magictrick, and the detection of a counterfeit coin. The article furtherelucidates the generalization of these puzzles using thebalanced number system.
pp 1411-1412 Crossword
pp 1413-1413 Information and Announcements
pp 1415-1415 Birds in the Backyard