• Comparative morphology of normal mammary glands of four strains of mice, varying in their susceptibility to breast cancer

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/secb/022/01/0018-0029

    • Keywords

       

      Mammary Gland; Side Branch; Normal Mammary Gland; Hyperplastic Nodule; Virgin Mouse

    • Abstract

       

      1. The detailed study of comparative morphology of mammary glands of four different strains C3H, A,dba and C57—from the ages of21/2 to 8 months shows that certain minor differences as regards the number of side branches, acinar clusters and dilatation of ducts are seen as early as21/2 to 3 months.

      2. The significant developmental differences leading to abnormal growth at a later age are exhibited at the age of 51/2 to 6 months between the strains C3H, A and C57 whiledba forms a class by itself. The structural peculiarities of different strains are seen at definitely advanced stage at a later age of 6 to 8 months.

      3. An attempt has been made to discuss the bearing of morphological differences on strain susceptibility to cancer.

    • Author Affiliations

       

      Kamal Ranadive1

      1. Department of Pathology, Tata Memorial Hospital, Pare I, Bombay
    • Dates

       
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