Comparative morphology of normal mammary glands of four strains of mice, varying in their susceptibility to breast cancer
The detailed study of comparative morphology of mammary glands of four different strains C3H, A,dba and C57—from the ages of21/2 to 8 months shows that certain minor differences as regards the number of side branches, acinar clusters and dilatation of ducts are seen as early as21/2 to 3 months.
The significant developmental differences leading to abnormal growth at a later age are exhibited at the age of 51/2 to 6 months between the strains C3H, A and C57 whiledba forms a class by itself. The structural peculiarities of different strains are seen at definitely advanced stage at a later age of 6 to 8 months.
An attempt has been made to discuss the bearing of morphological differences on strain susceptibility to cancer.