• Nuclear oxidation in flavones and related compounds - Part L. A Synthesis of Ravenelin

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    • Keywords


      Phloroglucinol; Xanthone; Zinc Chloride; Orcinol; Phosphorus Oxychloride

    • Abstract


      2-Hydroxy-6-methoxy benzoic acid condenses with orcinol giving rise to (1) 1-hydroxy-3-methyl-8-methoxy xanthone and (2) 1: 8-dihydroxy-3-methyl xanthone. The second is also obtained from γ-resorcylic acid. The first undergoes nuclear oxidation with alkaline persulphate to yield ravenelin-8-methyl ether which is demethylated to ravenelin.

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