• Synthetic experiments in the benzopyrone series - Part LIV. Nuclear methylation of simple flavonols

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/seca/040/06/0249-0259

    • Keywords

       

      Kaempferol; Methyl Alcohol; Galangin; Dimethyl Sulphate; Hydriodic Acid

    • Abstract

       

      3-Methoxy-7-hydroxy flavone does not undergo nuclear methylation. Nuclear methylation of (1) 3-O-methyl galangin and (2) 3:4′-O-dimethyl kaempferol has been shown to take place in the 6-position. As an intermediate in the case of (1) 3-O-methyl-6-C-methyl galangin has been isolated. The minimum structural requirements of this reaction and its mechanism are discussed.

    • Author Affiliations

       

      A C Jain1 T R Seshadri1

      1. From the Department of Chemistry, University of Delhi, Delhi
    • Dates

       
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