• Synthetical experiments in the chromone group - Part XXX. A synthesis of 3:5:8:3′:4′-pentahydroxyflavone and its non-identity with ponderosin

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    • Keywords


      Raney Nickel; Anhydrous Potassium Carbonate; Dimethyl Sulphate; Synthetical Experiment; Veratric Acid

    • Abstract


      By Raney nickel hydrogenolysis of the 7-tosyl ester (V), 5:7-dihydroxy-3: 3′:4′-trimethoxyflavone (IV) has been converted into 5-hydroxy-3:3′:4′-trimethoxyflavone (VI). Persulphate oxidation of (VI) gave 5: 8-dihydroxy-3: 3′:4′-trimethoxyflavone (VII), which was demethylated to 3:5:8:3′:4′-pentahydroxyflavone (III) by means of aluminium bromide in benzene. This pentahydroxyflavone was different in its properties from ponderosin, the yellow colouring matter ofPonderosa pine bark.

    • Author Affiliations


      V Ramanathan1 K Venkataraman1

      1. Department of Chemical Technology, University of Bombay, India
    • Dates


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