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      Permanent link:
      https://www.ias.ac.in/article/fulltext/seca/038/06/0480-0494

    • Keywords

       

      Flavone; Sodium Carbonate Solution; Dimethyl Sulphate; Acetoacetic Ester; Hydriodic Acid

    • Abstract

       

      The two higher analogues of 5-hydroxy flavone (primuletin) containing two and three methoxyl groups in the side phenyl nucleus have been synthesised and subjected to persulphate oxidation. 5-Hydroxy-3′:4′-dimethoxy flavone gave poor yield of dimethoxy primetin while the higher member could not be oxidised under these conditions. Alternatively, oxidation of 8-hydroxy flavones has been attempted and found to proceed more satisfactorily to yield primetin and its higher members. The required 8-hydroxy flavones have been made from 2:3-dihydroxy acetophenone for the preparation of which a convenient method has been worked out starting from ortho vanillin.

    • Author Affiliations

       

      V K Ahluwalia1 D S Gupta1 V V S Murti1 T R Seshadri1

      1. From the Chemistry Department, University of Delhi, Delhi
    • Dates

       
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