• Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/seca/036/03/0194-0200

    • Keywords

       

      Genistein; Monomethyl Ether; Hydrobromic Acid; Anhydrous Potassium Carbonate; Dimethyl Sulphate

    • Abstract

       

      It is shown that the most convenient method of preparing prunetin is by the partial demethylation of genistein trimethyl ether with hydrobromic or hydriodic acid under controlled conditions. The 5-methyl ether of genistein (isoprunetin) has now been synthesised by the methylation of 7:4′-O-dibenzyl genistein and subsequent debenzylation. Its properties are very different from those of prunetin and it yields a diethyl ether which could be independently prepared from genistein. The present work conclusively proves that prunusetin cannot be 5-O-methyl genistein (isoprunetin) and should be the same as prunetin.

    • Author Affiliations

       

      N Narasimhachari1 T R Seshadri1 S Sethuraman1

      1. From the Department of Chemistry, Delhi University, India
    • Dates

       
  •  

© 2021-2022 Indian Academy of Sciences, Bengaluru.