• Nuclear oxidation in flavones and related compounds - Part XXXVII. Isomerisation of 2:3-dimethyl-5:7:8-trihydroxy chromone

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/seca/035/02/0082-0088

    • Keywords

       

      Ferric Chloride; Chromone; Wogonin; Aqueous Sodium Hydroxide; Dimethyl Sulphate

    • Abstract

       

      When boiled with hydriodic acid, 2:3-dimethyl-5:7:8-trimethoxy chromone undergoes besides demethylation, isomeric change also, yielding 2:3-dimethyl-5:6:7-trihydroxy chromone, thus showing that a free hydrogen atom in the 3-position is not essential for this isomeric change to take place and that the nature of the substituent is also important. For purposes of comparison, 2:3-dimethyl-5:7:8-trihydroxy chromone has been obtained by demethylation of the above trimethyl ether with aluminium chloride and 2:3-dimethyl-5:6:7-trimethoxy chromone by independent synthesis using nuclear oxidation as a stage.

    • Author Affiliations

       

      S K Mukerjee1 T R Seshadri1 S Varadarajan1

      1. From the Department of Chemistry, Delhi University, Delhi
    • Dates

       
  •  

© 2021-2022 Indian Academy of Sciences, Bengaluru.