• Nuclear oxidation in flavones and related compounds - Part XXXVII. Isomerisation of 2:3-dimethyl-5:7:8-trihydroxy chromone

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    • Keywords


      Ferric Chloride; Chromone; Wogonin; Aqueous Sodium Hydroxide; Dimethyl Sulphate

    • Abstract


      When boiled with hydriodic acid, 2:3-dimethyl-5:7:8-trimethoxy chromone undergoes besides demethylation, isomeric change also, yielding 2:3-dimethyl-5:6:7-trihydroxy chromone, thus showing that a free hydrogen atom in the 3-position is not essential for this isomeric change to take place and that the nature of the substituent is also important. For purposes of comparison, 2:3-dimethyl-5:7:8-trihydroxy chromone has been obtained by demethylation of the above trimethyl ether with aluminium chloride and 2:3-dimethyl-5:6:7-trimethoxy chromone by independent synthesis using nuclear oxidation as a stage.

    • Author Affiliations


      S K Mukerjee1 T R Seshadri1 S Varadarajan1

      1. From the Department of Chemistry, Delhi University, Delhi
    • Dates


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