Synthetic experiments in the benzo-pyrone series - Part XVII. Some isoflavono-7:8-furans
L Ramachandra Row T R Seshadri
Click here to view fulltext PDF
Permanent link:
https://www.ias.ac.in/article/fulltext/seca/034/03/0187-0196
Two methods of synthesising isoflavonofurans of the angular type are examined. Starting from karanjic acid (VI) and passing through the intermediate (X), 2-methyl-isoflavono-7:8-furan (XI) is easily obtained. The alternative method which starts with 2-methyl-7-hydroxy-isoflavone (XII) and builds up the furan ring through the 8-aldehyde (XIII) is beset with difficulties. However if instead of the aldehyde, the corresponding ketone (8-acetyl derivative XVII) is employed the difficulties are eliminated and good yield of 2:β-dimethyl-isoflavono-7:8-furan (XIX) is secured.
Our thanks are due to the Imperial Chemical Industries, Ltd., and the National Institute of Sciences of India for the award of a Fellowship to one of us (L. R. R.).
L Ramachandra Row1 T R Seshadri1
© 2021-2022 Indian Academy of Sciences, Bengaluru.