Nuclear oxidation in flavones and related compounds - Part XXVIII. Synthesis of 6-hydroxy primetin
S Rajagopalan T R Seshadri S Varadarajan
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For the synthesis of 5∶6∶8-trihydroxy flavone (6-hydroxy primetin), the two stage ortho-oxidation process is applied to primetin monomethyl ether. A good yield of the 6-aldehyde is obtained, which undergoes oxidation to 5∶6-dihydroxy-8-methoxy flavone. Subsequent demethylation yields 6-hydroxy primetin. Its properties and reactions and derivatives are described.
S Rajagopalan1 T R Seshadri1 S Varadarajan1
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