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      Permanent link:
      https://www.ias.ac.in/article/fulltext/seca/024/02/0238-0242

    • Keywords

       

      Flavonol; Aqueous Sodium Hydroxide; Galangin; Benzyl Ether; Ketimine

    • Abstract

       

      A satisfactory procedure for the preparation of 2-hydroxy-ω∶3∶6-trimethoxy-4-benzyloxy-acetophenone is described. Oxidation of this to the 2∶5-dihydroxyketone (IV), its condensation with the anhydride and sodium salt of benzoic acid and subsequent demethylation yield 6∶8-dihydroxygalangin. This constitutes a simplified method for the synthesis of 5∶6∶7∶8-hydroxyflavonols and their methyl ethers.

    • Author Affiliations

       

      V D Nageswara Sastri1 T R Seshadri1

      1. Department of Chemistry, Andhra University, India
    • Dates

       
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