Synthesis of izalpinin
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Izalpinin (7-methyl ether of galangin) has been obtained by the demethylation of galangin di- and trimethyl ethers using both aluminium chloride and aluminium bromide. The synthetic sample has all the properties recorded for the naturally occurring substance. The condensation of ω:4:6-trimethoxy-phloroacetophenone with benzoic anhydride and sodium benzoate yields mainly 3:7-dimethyl ether of galangin.
K Visweswara Rao1 T R Seshadri1
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