• Synthesis of 6∶7-dihydroxy-flavonols - Part I. 6 ∶ 7 ∶ 3′ ∶ 4′-tetra-hydroxy-flavonol

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      https://www.ias.ac.in/article/fulltext/seca/021/04/0155-0161

    • Keywords

       

      Flavonol; Aqueous Sodium Hydroxide; Anhydrous Potassium Carbonate; Anhydrous Benzene; Dimethyl Sulphate

    • Abstract

       

      The synthesis and properties of 6 ∶ 7 ∶ 3′ ∶ 4′-tetrahydroxy-flavonol and of its derivatives are described. ω ∶ 4-Dimethoxy-2-hydroxy-acetophenone is oxidised with persulphate in alkaline medium to yield ω ∶ 4-dimethoxy-2 ∶ 5-dihydroxy-acetophenone which is then condensed with veratric anhydride and sodium veratrate. The new flavonol and its methyl and acetyl derivatives differ from patuletin and its derivatives.

    • Author Affiliations

       

      L Ramachandra Row1 T R Seshadri1

      1. Department of Chemistry, Andhra University, Andhra, India
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