• Chemotherapy of bacterial infections - IX. Synthesis of some sulphathiazole derivatives

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/seca/018/06/0355-0359

    • Keywords

       

      Thiazole; Isoamyl; Sulphanilamide; Dimethyl Sulphate; Ethyl Iodide

    • Abstract

       

      The synthesis of various derivatives of sulphathiazole with alkyl and substituted alkyl substituents at the ring nitrogen of the thiazole nucleus has been described. Of these compounds only the methyl derivative showed good therapeutic activity in experimental streptococcal, pneumococal and plague infections in mice.

    • Author Affiliations

       

      K Ganapathi1

      1. Department of Chemotherapy, Haffkine Institute, Parel, Bombay
    • Dates

       
  •  

© 2021-2022 Indian Academy of Sciences, Bengaluru.