• Bacterial chemotherapy, II: Synthesis of possible intestinal antiseptics of the sulphanilamide group

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    • Keywords


      Sulphonamide; Dilute Hydrochloric Acid; Alkyl Sulphate; Sulphapyridine; Thiazoline

    • Abstract


      Chiefly by the action of alkyl or aralkyl halides or the alkyl sulphates on the sulphanilamido heterocycles, a series of compounds, insoluble in alkali, has been obtained. Because of the likelihood of these not being absorbed from the intestine, which is alkaline in pH, the type of compounds synthesised are expected to prove particularly useful in infections of the intestinal tract.

    • Author Affiliations


      S Rajagopalan1

      1. Haffkine Institute, Bombay
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