• The reactivity of the double bond in coumarins and related unsaturated carbonyl compounds - Part VIII. Addition of cyanoacetamide to umbelliferone and its methyl ether

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/seca/015/06/0424-0428

    • Keywords

       

      Coumarin; Aqueous Sodium Hydroxide; Concentrate Sulphuric Acid; Mixed Melting Point; Aqueous Alkali

    • Abstract

       

      The addition of cyanoacetamide to the double bond of 7-methoxy and 7-hydroxycoumarins is very slow and it is attributed to the influence of the substituents which act as electron sources. On hydrolysis, the products yield the corresponding cyanoacetic acid and acetic acid derivatives the latter of which could also be obtained by the reduction of methoxy and hydroxy coumarin-4-acetic acids using sodium amalgam. These compounds do not fluoresce in solution.

    • Author Affiliations

       

      T R Seshadri1 V Venkateswarlu1

      1. Department of Chemistry, Andhra University, Waltair
    • Dates

       
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