Tall buildings are mainly designed to resist wind loads because wind-induced vibration is more critical for occupant’s comfort level on top of the building. Therefore, evaluation of wind-generated pressure is must for such type of tall buildings. Investigation of response due to wind loads on tall buildings is possible by employing numerical modelling such as computational fluid dynamic tools. Regular plan shape structure can be designed for wind load using various international standards and available literatures. In this research comparisonis made between four models in which model-A and B is having the regular shape while model-C and D are of irregular shape. These study is useful for the designer to evaluate the response of structures under strong wind conditions. The grid sensitivity and validation study are performed for rectangular shape tall buildings. Validation of the study shows that numerical simulation results are more or less identical with experimental results. In present research work selected building models have equal cross-sectional area and height. Numericalstudy performed by employing the k-ε turbulence model and the results are compared with the experimental findings. Out of all the four models, the Y-shape model with round in corners has a minimum base moment and the least coefficient of drag.