This paper proposes a structural design and multi-objective optimization of a two-degree-of-freedom (DOF) monolithic mechanism. The mechanism is designed based on compliant mechanism with flexure hinge and is compact in size (126 mm by 107 mm). Unlike traditional one-lever mechanisms, a new doublelever mechanism is developed to increase the working travel amplification ratio of the monolithic mechanism. The ideal amplification ratio, the working travel, the statics and the dynamics of the mechanism are taken into consideration. The effects of design variables on the output responses such as the displacement and first natural frequency are investigated via finite-element analysis based on response surface methodology. The fuzzy-logicbased Taguchi method is then used to simultaneously optimize the displacement and the first natural frequency. Experimental validations are conducted to verify the optimal results, which are compared to those of the original design. On using a finite-element method, the validation results indicated that the displacement and frequency are enhanced by up to 12.47% and 33.27%, respectively, over those of the original design. The experiment results are in a good agreement with the simulations. It also revealed that the developed fuzzy-logic-based Taguchi method is an effectively systematic reasoning approach for optimizing the multiple quality characteristics of compliant mechanisms. It was noted that the working travel/displacement of the double-levermechanism is much larger than that of the traditional one-lever mechanism. It leads to the conclusion that the proposed mechanism has good performances for manipulations and positioning systems.