Stochastic seismic analysis of long-span bridges with Carbon ﬁbre reinforced polymer (CFRP) cables are presented in this study through combination of the advantages of the perturbation based stochastic ﬁnite element method (SFEM) and Monte Carlo simulation (MCS) method. Jindo cable-stayed and Fatih Sultan Mehmet (Second Bosporus) suspension bridges are chosen as an example. Carbon ﬁbre reinforced polymer cable (CFRP) and steel cables are used separately, in which the cable’s cross sectional area is determined by the principle equivalent axial stiffness. Geometric nonlinear effects are considered in the analysis. Uncertainties in the material are taken into account and Kocaeli earthquake in 1999 is chosen as a ground motion. The efﬁciency and accuracy of the proposed algorithm are validated by comparing with results of MCS method. It can be stated that using of CFRP cables in long-span bridges subjected to earthquake forces is feasible.