In our study, a comparative analysis of different nucleon–nucleon (NN) interactions which are produced within the relativistic mean field (RMF) theory is performed under the optical model. The real potential is obtained using the double-folding model for four different effective NN interactions such as R3Y(HS), R3Y(Z), R3Y(W) and R3Y(L1). The theoretical results are compared with M3Y effective NN interaction results which are calculated using this work. The similarities and differences of the NN interactions are discussed, and alternative NN interactionst o M3Y are suggested.