In this work, we derive analytical solutions for static structure factor for homogeneous and isotropic solution composed of two components interacting with each other via simple van der Waals potential which isinversely proportional to the sixth power of the distance between the two components. We assume that the first component is the solvent and the second component is the dissolved material which has low concentration or density in comparison to the concentration of the solvent, i.e. dilute solution, which is common for macromolecular fluids. The presented solution is obtained using direct and inverse Fourier transforms in solving Ornstein–Zernike equations(OZE) for multicomponent systems. We calculated isothermal compressibilities as a function of concentration and comparison with other simulation and theoretical results are presented. We believe that the presented solution can be useful in studying biomolecular fluids and other soft matter fluids.