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    • Keywords


      Wavelet transform; principal component analysis; fluorescence.

    • Abstract


      Fluorescence characteristics of human breast tissues are investigated through wavelet transform and principal component analysis (PCA). Wavelet transform of polarized fluorescence spectra of human breast tissues is found to localize spectral features that can reliably differentiate different tissue types. The emission range in the visible wavelength regime of 500–700 nm is analysed, with the excitation wavelength at 488 nm using laser as an excitation source, where flavin and porphyrin are some of the active fluorophores. A number of global and local parameters from principal component analysis of both high- and low-pass coefficients extracted in the wavelet domain, capturing spectral variations and subtle changes in the diseased tissues are clearly identifiable.

    • Author Affiliations


      Anita Gharekhan1 Ashok N Oza1 M B Sureshkumar2 Asima Pradhan3 Prasanta K Panigrahi4 5

      1. Physics Department, C.U. Shah Science College, Ahmedabad 380 014, India
      2. Department of Physics, Faculty of Science, The M.S. University of Baroda, Vadodara 390 002, India
      3. Department of Physics and Centre for Laser Technology, Indian Institute of Technology, Kanpur 208 016, India
      4. Physical Research Laboratory, Ahmedabad 380 009, India
      5. Indian Institute of Science Education and Research (IISER), Mohanpur 741 252, Kolkata, India
    • Dates

  • Pramana – Journal of Physics | News

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      Posted on July 25, 2019

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