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      https://www.ias.ac.in/article/fulltext/pram/070/01/0183-0190

    • Keywords

       

      Thermal impact; spiking threshold; ion channel kinetics; synaptic transmission.

    • Abstract

       

      The effect of environmental temperature on neuronal spiking behaviors is investigated by numerically simulating the temperature dependence of spiking threshold of the Hodgkin-Huxley neuron subject to synaptic stimulus. We find that the spiking threshold exhibits a global minimum in a specific temperature range where spike initiation needs weakest synaptic strength, which form the engineering perspective indicates the occurrence of optimal use of synaptic transmission in the nervous system. We further explore the biophysical origin of this phenomenon associated with ion channel gating kinetics and also discuss its possible biological relevance in information processing in neuronal systems.

    • Author Affiliations

       

      Shenbing Kuang1 Jiafu Wang1 2 Ting Zeng1 Aiyin Cao1

      1. Department of Physical Science and Technology, Wuhan University of Technology, Wuhan, 430070, China
      2. State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan, 430070, China
    • Dates

       
  • Pramana – Journal of Physics | News

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