• Fulltext


        Click here to view fulltext PDF

      Permanent link:

    • Keywords


      Molecular motors; atomic force microscope (AFM); immobilization; biomolecular electronics and nanotechnology

    • Abstract


      The present study reports the covalent immobilization of myosin on glass surface andin-vitro motility of actin-myosin biomolecular motor. Myosin was immobilized on poly-L-lysine coated glass using heterobifunctional cross linker EDC and characterized by AFM. Thein-vitro motility of actin was carried out on the immobilized myosin. It was observed that velocity of actin over myosin increases with increasing actin concentration (0.4–1.0 mg/ml) and was found in the range of 0.40–3.25 μm/s. The motility of actinmyosin motor on artificial surfaces is of immense importance for developing nanodevices for healthcare and engineering applications

    • Author Affiliations


      Ellis Bagga1 Sunita Kumari1 Rajesh Kumar1 Rakesh Kumar1 R P Bajpai1 Lalit M Bharadwaj1

      1. Biomolecular Electronics and Nanotechnology Division, Central Scientific Instrument Organisation, Sector 30/C, Chandigarh - 160 030, India
    • Dates

  • Pramana – Journal of Physics | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2022-2023 Indian Academy of Sciences, Bengaluru.