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      https://www.ias.ac.in/article/fulltext/pram/065/05/0777-0786

    • Keywords

       

      Rotation of red blood cell; optical tweezers; dual optical trap

    • Abstract

       

      We have constructed a dual trap optical tweezers set-up around an inverted microscope where both the traps can be independently controlled and manipulated in all the three dimensions. Here we report our observations on rotation of red blood cells (RBCs) in a linearly polarized optical trap. Red blood cells deform and become twisted in hypertonic phosphate buffer saline and when trapped, experience an unbalanced radiation pressure force. The torque generated from the unbalanced force causes the trapped RBC to rotate. Addition of Ca++ ions in the solution, keeping the osmolarity same, makes the cell membranes stiffer and the cells deform less. Thus the speed of rotation of the red blood cells can be controlled, as less deformation and in turn less asymmetry in shape produces less torque under the radiation pressure resulting in slower rotation at the same laser power

    • Author Affiliations

       

      Manas Khan1 Samarendra K Mohanty1 2 A K Sood1 3

      1. Department of Physics, Indian Institute of Science, Bangalore - 560 012, India
      2. Biomedical Applications Section, Centre for Advanced Technology, Indore - 452 013, India
      3. Unit on Nanoscience and Technology-DST, Indian Institute of Science, Bangalore - 560 012, India
    • Dates

       
  • Pramana – Journal of Physics | News

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