In this paper we study second order non-linear periodic systems driven by the ordinary vectorp-Laplacian with a non-smooth, locally Lipschitz potential function. Our approach is variational and it is based on the non-smooth critical point theory. We prove existence and multiplicity results under general growth conditions on the potential function. Then we establish the existence of non-trivial homoclinic (to zero) solutions. Our theorem appears to be the first such result (even for smooth problems) for systems monitored by thep-Laplacian. In the last section of the paper we examine the scalar non-linear and semilinear problem. Our approach uses a generalized Landesman-Lazer type condition which generalizes previous ones used in the literature. Also for the semilinear case the problem is at resonance at any eigenvalue.