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      https://www.ias.ac.in/article/fulltext/jgen/099/0054

    • Keywords

       

      AHSA2 gene; heat stress; snapshot technology; single-nucleotide polymorphism.

    • Abstract

       

      Droughtmaster is a tropical breed of beef cattle that can survive in hot climates and easily adapt to torrid environments. These traits are important in livestock breeding. In this study, we genotyped five single-nucleotide polymorphisms (SNPs) of the AHSA2 gene from 190 cattle belonging to three different breeds (Droughtmaster, Angus and Simmental) by using snapshot technology. This work aimed to identify the valuable molecular marker of heat resistance in cattle. Results showed that Droughtmaster exhibited higher expected heterozygosity and polymorphic information content compared with the two other breeds. The AHSA2-1 locus deviated from the Hardy–Weinberg equilibrium in the Droughtmaster breed (P < 0.05). Two SNPs in Droughtmaster diverged significantly from Angus and Simmental. The SNPs were identified as AHSA2-3 and AHSA2-4, which were closely linked to the three breeds based on pair-wise FST. AHSA2-4 involved a missense mutation. In summary, the GG genotypes in AHSA2-3 and AHSA2-4 may be candidate genotypes associated with heat resistance traits and may serve as valuable genetic markers for breeding of heat-tolerant beef cattle in the future.

    • Author Affiliations

       

      SHU-ZHU CHENG1 E. GUANG-XIN1 CHENG-LI LIU1 WANG-DUI BASANG2 YAN-BIN ZHU2 RI-SU NA1 YAN-GUO HAN1 YAN ZENG1 XIAO WANG1 WEI-WEI NI1 BAI-GAO YANG1 XING-HAI DUAN1 ZE-HUI GUO1 MEIHUA SONG3 YONG-FU HUANG1

      1. College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivore, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing 400716, People’s Republic of China
      2. State Key Laboratory of Barley and Yak Germplasm Resources and Genetic Improvement (Tibet Academy of Agricultural and Animal Husbandry Science (TAAAS)), Lhasa 850002, Tibet, People’s Republic of China
      3. Qixia Manor Veterinary Station, Qixia, Shandong 265300, People’s Republic of China
    • Dates

       
  • Journal of Genetics | News

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