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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jgen/088/04/0495-0515

    • Keywords

       

      ocular angiogenesis; corneal neovascularization; retinal neovascularization; diabetic retinopathy; age-related macular degeneration; retinopathy of prematurity; VEGF; PEDF; Flt-1; Flk-1; endostatin; angiopoietin; erythropoietin; Tie2; inflammation; <

    • Abstract

       

      Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Pathologic angiogenesis in the eye can lead to severe visual impairment. In our review, we discuss the roles of both pro-angiogenic and anti-angiogenic molecular players in corneal angiogenesis, proliferative diabetic retinopathy, exudative macular degeneration and retinopathy of prematurity, highlighting novel targets that have emerged over the past decade.

    • Author Affiliations

       

      Yureeda Qazi1 Surekha Maddula1 Balamurali K. Ambati1

      1. Department of Ophthalmology, John Moran Eye Center, University of Utah, 65 Mario Capecchi Drive, Salt Lake City, UT-84132, USA

    • Dates

       
      Published
      December 2009
      Manuscript received
      27 August 2009
      Manuscript revised
      22 October 2009
      Accepted
      26 October 2009
      Early published
      31 December 2009

  • Journal of Genetics | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

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