• The Drosophila melanogaster circadian pacemaker circuit

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jgen/087/05/0485-0493

    • Keywords

       

      circadian rhythm; neuronal network; ion channel; behaviour; neurotransmitter; electrophysiology; Drosophila.

    • Abstract

       

      As an experimental model system, the fruit fly Drosophila melanogaster has been seminal in shaping our understanding of the circadian clockwork. The wealth of genetic tools at our disposal over the past four decades has enabled discovery of the genetic and molecular bases of circadian rhythmicity. More recently, detailed investigation leading to the anatomical, neurochemical and electrophysiological characterization of the various neuronal subgroups that comprise the circadian machinery has revealed pathways through which these neurons come together to act as a neuronal circuit. Thus the D. melanogaster circadian pacemaker circuit presents a relatively simple and attractive model for the study of neuronal circuits and their functions.

    • Author Affiliations

       

      Vasu Sheeba1

      1. Poornaprajna Institute of Scientific Research, #4, Sadashivanagar, Bengaluru 560 080, India
    • Dates

       
  • Journal of Genetics | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2021-2022 Indian Academy of Sciences, Bengaluru.