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      https://www.ias.ac.in/article/fulltext/jgen/087/05/0459-0466

    • Keywords

       

      electroretinogram (ERG); retina; circadian; rhythm; melanopsin.

    • Abstract

       

      Circadian clocks are thought to regulate retinal physiology in anticipation of the large variation in environmental irradiance associated with the earth’s rotation upon its axis. In this review we discuss some of the rhythmic events that occur in the mammalian retina, and their consequences for retinal physiology. We also review methods of tracing retinal rhythmicity in vivo and highlight the electroretinogram (ERG) as a useful technique in this field. Principally, we discuss how this technique can be used as a quick and noninvasive way of assessing physiological changes that occur in the retina over the course of the day. We highlight some important recent findings facilitated by this approach and discuss its strengths and limitations.

    • Author Affiliations

       

      Morven A. Cameron1 Alun R. Barnard2 Robert J. Lucas1

      1. Faculty of Life Sciences, A. V. Hill Building, University of Manchester, Manchester M13 9PT, UK
      2. Neurobehaviour Group, MRC Harwell, Harwell, Didcot, Oxfordshire OX11 0RD, UK
    • Dates

       
  • Journal of Genetics | News

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      Posted on July 25, 2019

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