• Genotype–environment interaction for total fitness in Drosophila

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    • Keywords


      antagonistic pleiotropy; balancer chromosomes; environmental heterogeneity; maintenance of genetic variation; trade-offs.

    • Abstract


      A fundamental assumption of models for the maintenance of genetic variation by environmental heterogeneity is that selection favours different genotypes in different environments. Here, I use a method for measuring total fitness of chromosomal heterozygotes in Drosophila melanogaster to assess genotype–environment interaction for fitness across two ecologically relevant environments, medium with and without added ethanol. Two-third chromosomes are compared, one from a population selected for ethanol tolerance, and the other from a control population. The results show strong crossing of reaction norms for outbred, total fitness, with the chromosome from the ethanol-adapted population increasing fitness on ethanol-supplemented food, but decreasing fitness on regular food, relative to the chromosome from the control population. Although I did not map the fitness effects below the chromosome level, the method could be adapted for quantitative trait locus mapping, to determine whether a substantial proportion of fitness variation is contributed by loci at which different alleles are favoured in different environments.

    • Author Affiliations


      James D. Fry1

      1. Department of Biology, University of Rochester, Rochester NY 14627-0211, USA
    • Dates

  • Journal of Genetics | News

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      Posted on July 25, 2019

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