Cloning, chromosome localization and features of a novel human gene,MATH2
Lingchen Guo Min Jiang Yushu Ma Haipeng Cheng Xiaohua Ni Yangsheng Jin Yi Xie Yumin Mao
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We report cloning and some features of a novel human gene,MATH2, which encodes a protein of 337 amino acid residues with a basic helix-loop-helix domain and exhibits 98% similarity to mouseMath2. Results of Northern blot analysis revealed two transcripts of theMATH2 gene of 1.7 kb and 2.4 kb in human brain. We localizedMATH2 to chromosome 7 at 7p14-15 by matching with the Human Genome Sequence Database. HumanMATH2 and mouseMath2 may have the same functions in the nervous system.
Lingchen Guo1 Min Jiang1 Yushu Ma1 Haipeng Cheng1 Xiaohua Ni1 Yangsheng Jin2 Yi Xie1 Yumin Mao1
Volume 102, 2023
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