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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jgen/081/01/0013-0017

    • Keywords

       

      MATH2 ; transcription factor; bHLH; novel human gene

    • Abstract

       

      We report cloning and some features of a novel human gene,MATH2, which encodes a protein of 337 amino acid residues with a basic helix-loop-helix domain and exhibits 98% similarity to mouseMath2. Results of Northern blot analysis revealed two transcripts of theMATH2 gene of 1.7 kb and 2.4 kb in human brain. We localizedMATH2 to chromosome 7 at 7p14-15 by matching with the Human Genome Sequence Database. HumanMATH2 and mouseMath2 may have the same functions in the nervous system.

    • Author Affiliations

       

      Lingchen Guo1 Min Jiang1 Yushu Ma1 Haipeng Cheng1 Xiaohua Ni1 Yangsheng Jin2 Yi Xie1 Yumin Mao1

      1. State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai - 200433, People’s Republic of China
      2. United Gene Holdings, Ltd, Shanghai - 200092, People’s Republic of China

    • Dates

       
      Published
      April 2002
      Manuscript received
      14 December 2001

  • Journal of Genetics | News

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      Posted on July 25, 2019

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