The temperature field within the crust is closely related to tectonic history as well as many other geological processes inside the earth. Therefore, knowledge of the crustal thermal structure of a region is of great importance for its tectonophysical studies. This work deals with the two-dimensional thermal modelling to delineate the crustal thermal structure along a 230 km long Deep Seismic Sounding (DSS) profile in the north Cambay basin. In this work P-wave velocities obtained from the DSS studies have been converted into heat generation values for the computation of temperature distribution. The model result reveals the Curie isotherm at a depth of ≈22 km and Moho temperature at around 900‡C.