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    • A facile and efficient synthesis of Bis-thiazole from mono-thiazole

      MONIKA BANSAL

      Volume 134 Published: 4 March 2022 Article ID 0036

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/134/0036

    • Keywords

       

      One pot synthesis; Mono-thiazole; Bis-thiazole

    • Abstract

       

      This paper describes a facile route for the synthesis of bis-thiazoles from mono-thiazole with aneco-friendly method. The synthetic procedure for the synthesis of bis-thiazoles from the reaction of 2-amino-4-tolyl thiazole with different aromatic aldehydes under microwave irradiations is discussed. Structures of thefinal products are characterized by IR, 1H and 13C- NMR spectra, DEPT-135 and mass spectrometry.

    • Graphical Abstract

       

      A facile method is developed to synthesis bis-amino thiazole from easily synthesised mono thiazole. A series of bis thiazole were obtained with free amino groups which can be used for late-stage synthesis of new bis heterocyclic compounds.

    • Author Affiliations

       

      MONIKA BANSAL1

      1. Department of Chemistry, GSSDGS Khalsa College, Patiala, Punjab 147001, India

    • Dates

       
      Published
      4 March 2022
      Manuscript received
      19 October 2021
      Manuscript revised
      19 October 2021
      Accepted
      22 December 2021

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