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      https://www.ias.ac.in/article/fulltext/jcsc/134/0023

    • Keywords

       

      Rhodium; iridium; 4,5 diazafluorene-9-one; antibacterial; antioxidant.

    • Abstract

       

      Reaction of [(arene)MCl2]2 with bidentate 4, 5-diazafluorene-9-one (dafo) and derived Schiff base ligands (L1–L3) in the presence of ammonium hexafluorophosphate yielded mononuclear cationic complexes having general formula [(arene)MLCl]PF6 {M = Ru, arene = benzene (1, 5, 9); M = Ru, arene = p-cymene (4, 8); M = Rh, arene = Cp* (2, 6, 10); M = Ir, arene = Cp* (3, 7, 11); L = 4, 5-diazafluorene-9-one(L1), N-(4, 5-diazafluoren-9-ylidene)aniline (L2), N-(4, 5-diazafluoren-9-ylidene)phenyl hydrazine (L3)}.All these complexes were isolated as hexafluorophosphate salts and characterized by spectral and analyticaltechniques such as FT-IR, UV-vis, NMR spectroscopy and ESI-Mass spectrometry. Complexes 1-3 werecharacterized by X-ray crystallographic studies, which indicated NN0 bidentate coordination of the ligandsthrough pyridine nitrogen atoms of the ligand. To evaluate the biological properties of these complexes,antibacterial and antioxidant experiments have been carried out. The complexes 8, 9 and 11 exhibitedantibacterial activity against Gram-positive bacteria. Results also show that the compounds possess prominentantioxidant activity against DPPH radicals.

    • Graphical Abstract

       

      The reaction of [(arene)MCl2]2 with 4, 5- diazafluorene-9-one (dafo) and derived Schiff-base ligands yielded mononuclear cationic complexes having the general formula [(arene)MLCl]PF6-. Some of the complexes exhibited antibacterial activity against Gram-positive bacteria. Results also show that the compounds possess prominent antioxidant activity against DPPH radicals.

    • Author Affiliations

       

      CARLEY GIFFERT L NONGPIUR1 DEEPAK KUMAR TRIPATHI2 KRISHNA MOHAN POLURI2 HEMANT RAWAT3 MOHAN RAO KOLLIPARA1

      1. Centre for Advanced Studies in Chemistry, North-Eastern Hill University, Shillong 793 022, India
      2. Department of Biotechnology and Centre for Nanotechnology, Indian Institute of Technology Roorkee, Roorkee 247 667, India
      3. Central Ayurveda Research Institute, Jhansi 284003, India
    • Dates

       
  • Journal of Chemical Sciences | News

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