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https://www.ias.ac.in/article/fulltext/jcsc/132/0145

Catalysis; Diels–Alder reaction; enyne metathesis; natural product

Development of a route for the synthesis of the core structure of galiellalactone is described. The key step involves a ring-closing enyne metathesis of an allyl propargyl ether to produce a dihydro furano diene with a latent dienophile. The dienophile, when generated from this latent functionality, underwent an in situ intramolecular Diels–Alder reaction to produce the tricyclic skeleton present in galiellalactone

RITABRATA DATTA SUBRATA GHOSH¹

1. School of Chemical Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700 032, India

Published

31 October 2020

Manuscript received

25 June 2020

Manuscript revised

6 August 2020

Accepted

10 August 2020