• Sequential ring-closing enyne metathesis and intramolecular Diels– Alder reaction: an approach to the synthesis of the core structure of galiellalactone

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    • Keywords


      Catalysis; Diels–Alder reaction; enyne metathesis; natural product

    • Abstract


      Development of a route for the synthesis of the core structure of galiellalactone is described. The key step involves a ring-closing enyne metathesis of an allyl propargyl ether to produce a dihydro furano diene with a latent dienophile. The dienophile, when generated from this latent functionality, underwent an in situ intramolecular Diels–Alder reaction to produce the tricyclic skeleton present in galiellalactone

    • Author Affiliations



      1. School of Chemical Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700 032, India
    • Dates

  • Journal of Chemical Sciences | News

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