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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/132/0078

    • Keywords

       

      Heterogeneous catalysis; AS@HTC; N-alkylation; pyrimidines

    • Abstract

       

      An efficient and inexpensive method for the N-alkylation of pyrimidines using ammonium sulfate coated Hydro-Thermal-Carbone (HTC) (AS@HTC) as reused heterogeneous catalyst was developed. The catalyst was characterized by several analytical techniques such as SEM, XRD, and FTIR. The effect ofvarious parameters was studied including catalyst loading, mole ratio, to achieve excellent selectivity and yields in 80–90%. Significantly, the present protocol offers the use of an inexpensive and environmentally friendly catalyst and simple workup. The simplicity of the procedure, excellent yield of the products, and therecyclability of the catalyst are the main advantages of this method.

    • Author Affiliations

       

      SOUMIA BELKHARCHACH1 HANA IGHACHANE1 ABDESSADEK LACHGAR2 MUSTAPHA AIT ALI3 HASSAN B LAZREK1

      1. Laboratory of Biomolecular and Medicinal Chemistry, Faculty of Science Semlalia, 40000 Marrakech, Morocco
      2. Department of Chemistry, Wake Forest University, Winston Salem, NC, USA
      3. Laboratory of Coordination Chemistry and Catalysis, Faculty of Science Semlalia, 40000 Marrakech, Morocco
    • Dates

       
  • Journal of Chemical Sciences | News

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