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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/132/0063

    • Keywords

       

      Heterocyclic chemistry; 1,3-Hydride transfer; Mechanistic study; Isoindole-fused quinazolinones.

    • Abstract

       

      One-pot synthesis of isoindole fused quinazolin 4-ones via intramolecular 1,3 hydride transfer in the presence of acid catalyst has been described. Substrate scope and mechanistic insights were investigated. Substituents on the amide side have a negligible influence on the key step and therefore the method have widescope for accessing various bicyclic core structure.

    • Author Affiliations

       

      MOHABUL A MONDAL1 SUDIPTA MONDAL ABDUL A KHAN

      1. Department of Chemistry, Jadavpur University, Kolkata 700 032, West Bengal, India

    • Dates

       
      Published
      16 April 2020
      Manuscript received
      20 June 2019
      Manuscript revised
      22 November 2019
      Accepted
      2 January 2020

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