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    • Iodine-catalyzed regioselective C-3 arylation of indoles with pquinols

      NEHA DUA RAMA KRISHNA PEDDINTI

      Volume 132 Published: 27 February 2020 Article ID 0045

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      https://www.ias.ac.in/article/fulltext/jcsc/132/0045

    • Keywords

       

      C-3 arylation of indoles; meta-functionalized phenols; indole-phenol hybrids; regioselective reaction.

    • Abstract

       

      Iodine-mediated highly convenient strategy for the C-3 arylation of indoles with p-quinols is presented. The present work surpasses in forming a C–C bond at the meta-position of the phenols, which is traditionally challenging to functionalize. This protocol further leads the way to have ascendable, forthright access to phenol-assimilated heterocycles which have powerful applications both in synthetic and medicinal chemistry.

    • Author Affiliations

       

      NEHA DUA RAMA KRISHNA PEDDINTI1

      1. Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand 247 667, India

    • Dates

       
      Published
      27 February 2020
      Manuscript received
      14 May 2019
      Manuscript revised
      21 October 2019
      Accepted
      4 November 2019

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