Click here to view fulltext PDF

Permanent link:
https://www.ias.ac.in/article/fulltext/jcsc/132/0031

Squaric acid; organocatalyst; 2,3-dihydro-1H-perimidines; green chemistry

Squaric acid, a green, metal-free and eco-friendly organocatalyst, has been exploited for the synthesis of biologically interesting 2,3-dihydro-1H-perimidines. The reaction was performed using water as a green reaction medium and the organocatalyst can be easily recovered and reused up to four consecutivecycles without much decrease in catalytic activity. Several advantages of the present methodology are low catalyst loading, excellent catalytic performance, easy catalyst handling, mild reaction conditions, operational simplicity, ease of product isolation, avoidance of column chromatographic separation, a higher yield of the desired product in short reaction time, high atom economy and synthesis of benzophenone based perimidine

SUSHIL KHOPKAR GANAPATI SHANKARLING

Published

25 January 2020

Manuscript received

8 May 2019

Manuscript revised

23 September 2019

Accepted

13 October 2019