Squaric acid: an impressive organocatalyst for the synthesis of biologically relevant 2,3-dihydro-1H-perimidines in water
SUSHIL KHOPKAR GANAPATI SHANKARLING
Click here to view fulltext PDF
Permanent link:
https://www.ias.ac.in/article/fulltext/jcsc/132/0031
Squaric acid, a green, metal-free and eco-friendly organocatalyst, has been exploited for the synthesis of biologically interesting 2,3-dihydro-1H-perimidines. The reaction was performed using water as a green reaction medium and the organocatalyst can be easily recovered and reused up to four consecutivecycles without much decrease in catalytic activity. Several advantages of the present methodology are low catalyst loading, excellent catalytic performance, easy catalyst handling, mild reaction conditions, operational simplicity, ease of product isolation, avoidance of column chromatographic separation, a higher yield of the desired product in short reaction time, high atom economy and synthesis of benzophenone based perimidine
Volume 132, 2020
All articles
Continuous Article Publishing mode
Click here for Editorial Note on CAP Mode
© 2021-2022 Indian Academy of Sciences, Bengaluru.