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      https://www.ias.ac.in/article/fulltext/jcsc/131/10/0105

    • Keywords

       

      Pyrazolone; silica-supported zinc chloride catalyst; green synthesis; anti-oxidant activity

    • Abstract

       

      The present research work deals with the green synthesis of substituted pyrazolone derivatives 4(a–f) from 2,4-dinitrophenylhydrazine with various substituted aromatic aldehyde and ethyl acetoacetate in the presence of silica-supported zinc chloride (SiO2/ZnCl2) as a recyclable Lewis acid catalyst. The synthesized compounds were structurally characterized with IR, 1H NMR, Mass spectra and elemental analysis. All these compounds were tested for their antioxidant activity by using the DPPH radical scavenging method.

    • Author Affiliations

       

      G NEELIMA1 K LAKSHMI2 K SESHA MAHESWARAMMA3

      1. JNTU, Ananthapuramu, Anantapur, India
      2. Department of Pharmaceutical Analysis, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor, Andhra Pradesh 517 127, India
      3. Department of Chemistry, JNTU College of Engineering (Autonomous) Pulivendula, Pulivendula, Andhra Pradesh 516 390, India
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    • Supplementary Material

       
  • Journal of Chemical Sciences | News

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