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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/131/09/0089

    • Keywords

       

      MRI; nanoparticles; magnetic field; relaxivity.

    • Abstract

       

      In the near future there would be a need for a high field MRI contrast agent for the MRI diagnostic due to the several disadvantages of Gd-based complexes, such as short circulation time and decrease in efficiency at high magnetic field i.e., greater than 3 T. The lanthanide-based nanoparticle can be an alternative to these complexes due to a high density of metal ions per unit of contrast agent. The high density of the metal ions will enable the MR signal shortening usually, at lower concentrations compared to chelates that typically are used at micro-molar concentrations. Additionally, the nanoparticles would retain their relaxivity efficiency at high magnetic field greater than 3 T

    • Author Affiliations

       

      ANURAG GAUTAM1 PRAGYA KOMAL2 RAM SEVAK SINGH1

      1. School of Science, O. P. Jindal University, Raigarh 496001, Chhattisgarh, India
      2. Department of Biology, Birla Institute of Technology and Science, Pilani-Hyderabad Campus, Jawaharnagar, Shamirpet Mandal, Hyderabad 500078, Telangana, India

    • Dates

       
      Published
      September 2019
      Manuscript received
      31 March 2019
      Manuscript revised
      13 May 2019
      Accepted
      15 May 2019

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