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      https://www.ias.ac.in/article/fulltext/jcsc/131/08/0081

    • Keywords

       

      Ruthenium(II) complex; binuclear Ni(II) complex; pyridine dicarboxylic acid; NMR; X-ray crystallography; cyclic voltammetry; CT-DNA; BSA.

    • Abstract

       

      An attempt to synthesize mixed geometrical hetero binuclear complexes has been made by reacting 2,6 pyridinedicarboxylic acid with [NiCl2(PPh3)2] and [RuHCl(CO)(PPh3)3]. However, the reaction afforded a mononuclear complex [Ru(dipic)(CO)(PPh3)2].DMF (1) and homo binuclear complex [Ni2(-dipic)2(H2O)5].2H2O (2) [dipic = 2,6-pyridinedicarboxylate] respectively. The new complexes (1 and 2) were characterized by elemental analyses, IR, UV-Vis, 1H-NMR and single-crystal X-ray diffraction studies. The complexes 1 and 2 crystallized in the monoclinic P21/c and triclinic P-1 space groups, respectively. Complex 2 displayed a three-dimensional (3D) network with lattice water molecules. The redox behaviour of the complexes was studied by cyclic voltammetry. The DNA and albumin binding studies of the complexes weredone by taking CT-DNA and BSA as models. The new complexes exhibited significant binding efficiency with DNA and albumin.

    • Author Affiliations

       

      P KALAIVANI1 H PUSCHMANN2 M V KAVERI3 T SURESH3 R PRABHAKARAN3

      1. Department of Chemistry, Nirmala College for Women, Bharathiar University, Coimbatore, Tamilnadu 641018, India
      2. Department of Chemistry, Durham University, Durham DH1 3LE, UK
      3. Department of Chemistry, Bharathiar University, Coimbatore, Tamilnadu 641 046, India
    • Dates

       
  • Journal of Chemical Sciences | News

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